Studies in English

Prof. Miloš Korać, MD, PhD- course director

Assoc. Prof. Jasmina Poluga, MD, PhD

Assoc. Prof. Goran Stevanović, MD, PhD

Assoc. Prof. Jovan Ranin, MD, PhD

Assoc. Prof . Ivana Milošević, MD,PhD

Asst. Nataša Nikolić, MD,PhD

Asst. Nikola Mitrović, MD,PhD

Asst. Jelena Jordović, MD,PHD

Asst. Jovan Malinić, MD

Asst. Marko Marković, MD

Asst. Uroš Karić

Asst. Aleksandra Barać

Asst. Boris Jegorović

Asst. Ankica Vujović

 

SYLLABUS OF LECTURES

Winter semester

1. Introduction to infectious diseases -principals of diagnosis, therapy and

prevention

2. Streptococcal infections

3. Immunization principles and vaccine use

4. Staphylococcal infections

5. Aproach to the acutelly ill infected febrile patient

 

6. Gastrointestinal infections I (food poisoning, dysentery, Clostridium diff. infection)

7. Gastrointestinal infections II (typhoid fever, salmonelloses, cholera)

8. Respiratory viral infections, influenza

9. Pneumonia

10. Urinary tract infections

 

11. Haemorrhagic fevers

12. Variola, measles, rubella,

13. Infectious mononucleosis, CMV infection, HSV infections

14. Chickenpox, 5th and 6th disease

A Guide to Studies in English - 1st year 39

Summer semester

1. Infections in pregnancy

2. Intrahospital infections

3. Approach to the patient with liver disease

4. Acute viral hepatitis

5. Chronic hepatitis B

6. Chronic hepatitis C

7. Introduction: Infections of CNS

8. Viral meningitis and Encephalitis

9. Bacterial meningitis

10. Focal infections of CNS

11. Enteroviral infections

12. TBC meningitis

13. Septicemia

14. Septic shock

15. Metazoal infections

16. Giardiasis, amoebiasis Leishmaniasis

17. Introduction: HIV infection

18. AIDS

19. Malaria

20. Ricketial infections

21. Anaerobic infections (tetanus, botulismus, gas gangrene)

22. FUO (fever of unknown origine)

23. Toxoplasmosis

24. Anthrax, brucellosis, tularemia

 

 

SYLLABUS OF PRACTICALS IN VII AND VIII SEMESTER

Practical course part is organized at different hospital ward each week,so that during the semester students have the opportunity to visit all wards at least twice. Due to the seasonal nature of some infectious diseases, students will be presented with interesting cases regardless of the schedule. For the same reason, type of patients on some wards varies considerably, so that students can encounter very different and / or rare infectious disease.

 

Introductory classes

1. Medical history (demonstration of the patient with infectious disease -case report)

2. The condition of the patient with infectious disease (demonstration with case report)

3. Outpatient department:

• getting acquainted with organization of outpatient department work,
• history taking and examination of 2-3 patients, taking basic laboratory tests
• writing outpatient departmenti report
• getting acquainted with basic principles of prevention and specific prophylaxis
• getting acquainted with invasive diagnostic procedures (gastroduodenoscopy,

liver biopsy, laparascopy, colonoscopy... )

4. Intensive care

• Acute viral encfalitis
• medical history  (conscious patients) and condition of severe patients (special emphasis on neurological finding)
• diagnosis:lumbal punction, liquor test, CT, MR analysis , analysis of serous results...
• therapy: measures of intensive treatment
• acute bacterial meningoencefalitis (history taking, state, differential diagnostics, therapy ...)
• sepsis-history taking, physical finding, diagnostics, diferential diagnostics,
• critically ill vague patients
• therapeutical approach

5. Department of CNS infections

• bacterial (piogenic or TB) meningitis, viral meningitis (history taking,risk factors, state -emphasis on neurological finding )
• diagnosis (lumbal punction, interpretation of results)
• therapeutical procedures

6. Unclear febrile conditions

• medical history, epidemiological characteristics, approach to unclear febrile condition -state, diagnosis and differential diagnosis, interpretation of laboratory results and examinations -therapeutically procedures

7. Center for HIV and AIDS

• medical history and physical examination
• diagnosis, differential diagnosis, interpretation of laboratory findings and performed examinations
• therapeutically approach

8. Department of gastrointestinal infections

• medical history and physical examination
• diagnosis, differential diagnosis, interpretation of laboratory findings and performed examinations
• therapeutically approach

9. Department of hepatitis

• medical history, physical examination
• basic diagnostic principles, differential diagnosis, interpretation of laboratory findings and performed examinations
• therapeutically approach

 

 

Schedule of colloquia:

I colloquium- end of December

II colloquium - beginning of February

III colloquium -end of April

Schedule of Seminars :

1. Fever of unknown origin

2. Lymphadenopathy in infectious diseases

3. Fever and rash

4. Infective andocarditis

5. Infections in trasnplant recipients

 

 

ELECTIVE CLASSES

 

Subject: DIAGNOSIS AND TREATMENT OF CHRONIC VIRAL LIVER DISEASE

 

Curriculum:

1.            Epidemiological characteristics of viral hepatitis (means of transmission, prevention...)                                                                                                      1 hour

2.            Clinical features of viral hepatitis                                                                   1 hour

3.            The role of biochemical parameters in the diagnosis of viral hepatitis   1 hour

4.            Serological and virological diagnosis of viral hepatitis                                1 hour

5.            The importance of echosonography in viral liver diseases                         1 hour

Invasive and non-invasive diagnostics (liver biopsy, APRI score, fibrosken, fibromax...)                                                                                                          1 hour                                                                                                                                    

6.      Histopatological characteristics of acute and chronic viral hepatitis         1 hour             

7.  Chronic B hepatitis (diagnosis, pathogenesis, therapy, special groups of      patients..)                                                                                                                      2 hours

8. Chronic C hepatitis (diagnosis, pathogenesis, therapy, extrahepatic manifestations, special groups of patients ......)                                             2 hours                                                               

9.     Hepatocellular carcinoma (diagnosis, therapy..)                                           1 hour

10.  Antiviral therapy (indications, protocols, patient evaluation.......)             1 hour               

 

Lecture structure:

1-3. hours	Epidemiological and Clinical features of viral hepatitis                                                               (definition, means of transmission, prevention                                      etiology, classification, pathogenesis, clinical picture, diagnosis, dif. diagnosis, prognosis, ..)
4-6. hours	Diagnostics of viral hepatitis (biochemical, serological and virological parameters.)
7-9. hours	Diagnostics of viral hepatitis -invasive (liver biopsy) and -non-invasive diagnostics (echosonography, fibrosken,    fibromax...)     -histopatology of viral hepatitis
10-12. hours	Chronic B hepatitis (diagnosis, pathogenesis, therapy, special groups of patients..)
13-15. hours	Chronic C hepatitis (diagnosis, pathogenesis, therapy, extrahepatic manifestations, special groups of patients ......)
16-18. hours	Hepatocellular carcinoma (diagnosis, therapy..)                                      Antiviral therapy (indications, protocols, patient evaluation...)
19.21. hours	Practical work with patients in the ward
22-24. hours	Practical work with patients in the ward
25-27. hours	Patient discussion and case reports
28-30. hours	Patient discussion and case reports discussion about the performed course

 

 

Subject: MORBIDITY AND MORTALITY FROM HIV DISEASE IN THE ERA OF COMBINED ANTIRETROVIRAL TREATMENT

 

Lecture structure:

1-3. hours	Lecture: definition, epidemiology, etiology, classification, pathogenesis, clinical picture, diagnosis, dif. diagnosis, treatment, comorbidity, prognosis of HIV disease
4-6. hours	Clinical semiotics of HIV disease then and now
7-9. hours	Co-infections
10-12. hours	HIV and hepatitis B and C
13-15. hours	HIV and TB
16-18. hours	Practical work with patients in the ward and clinic
19.21. hours	Practical work with patients in the ward and clinic
22-24. hours	Patient discussion
25-27. hours	Patient discussion
28-30. hours	Patient discussion, discussion about the performed course

 

 

Getting points and obtaining final grade

1.    Points for passive and active participation on practicals and lectures

-        All...................10

 

2.    Colloquiums    

Maximum number of points for 3 colloquiums (3x10) is 20.

Everything else is recalculated by proportion, in case the student has at least 16 correct answers of 30 (>50%) in each colloquium.

Missed colloquium is 0 points

 

3.     Practical exam

During the practical exam,  teacher is getting insight into student's knowledge and skills in infectious diseases. Practical exam consists of :

1.    complete history of illness

2.    complete examination including rough neurological examination and meningeal signs

3.    presentation of the patient to examiner

Maximum number of points for the practical exam is 20. Practical note 5= 0 pt.

Points	Note
20	10
18	9
16	8
14	7
12	6

Practical note 5= 0 pt.

 

4. Final Test

Participation in the final test requires a previously passed practical exam

Maximum number of points for the final test  is 50.

Everything else is recalculated by proportion, in case the student has >50% correct answers

 

 

5.Final grade

 

Final grade  is composed from the points obtained on colloquiums, practical exam and final  test including activity, and is derived from total points as follows.

 

TOTAL POINTS	FINAL GRADE
91-100	10
81-90	9
71-80	8
61-70	7
51-60	6
<51	5

 

EXAM QUESTIONS -INFECTIOUS DISEASES

 

 

GENERAL INFECTOLOGY

1. General characteristics of infectious syndrome

2. Angina syndrom

3. Meningeal syndrome

4. Lumbal punction and liquor exam

5. Rash in infectious diseases

6. Acute diarrhoeal syndrome in infectious diseases

7. Chronic diarrhoeal syndrome in infectious diseases

8. Icterus in infectious disseases

9. Lymphadenopathy in infectious diseases

10. Clinical diagnostics of infectious diseases

11. Biochemical and hematologaical diagnostics of infectious diseases

A Guide t 44 o Studies in English - 1st year

12. Bacteriological diagnostics of infectious diseases

13. Diagnostics of parasite infections

14. Diagnostics of viral infections

15. Principles of antimicrobial therapy of infectious diseases

16. Passive and active protection from infectious diseases

 

SPECIIAL INFECTOLOGY

17. Etiology and pathogenesis of bacterial meningitis

18. Clinical picture of bacterial meningitis

19. Liquor finding in bacterial meningitis

20. Therapy of bacterial meningitis

21. Meningococcal meningitis

22. Meniingococcal disease

23. Pneumococcal meningitis

24. Meningitis induced by Hemofilus influence type b

25. Antibiotic therapy and prophylaxis of bacterial meningitis

26. Focal bacterial infections of endocranium

27. TB meningitis

28. Differential diagnosis of bacterial meningitis

29. Complications of bacterial meningitis

30. Etiology and clinical picture of viral meningitis

31. Liquor finding in viral meningitis

32. Acute viral encephalitis

33. Clinical picture and complications of acute viral encephalitis

34. Diagnosis and differential diagnosis of acute viral encephalitis

35. Rabies

36. Slow viral infections

37. Bacterial pharyngitis

38. Diphtheria

39. Differential diagnosis of pharyngitis

40. Pertussis

41. Pneumonia, Legionnaires' disease

42. Psittacosis

43. Influenza

44. Etiology and clinical picture of respiratory viral infections

45. Mumps infection

46. Clinical picture and complications of mumps infection

47. Colera

48. Traveller's diarrhoea

49. Viral infections of digestive system

50. Food intoxication - alimentary intoxication

51. Fungus intoxication

52. Helicobacteriosis

53. Campylobacteriosis

54. Yersiniosis

55. Infections of digestive system caused by E.coli

56. Amoebic dysentery

57. Bacillary dysentery

58. Salmonellosis

59. Typhoid and paratyphoid

60. Lambliasis

61. The principles of treatment of acute infectious diarrheal syndrome

62. Etiology and epidemiology of viral hepatitis

63. The clinical features of acute viral hepatitis

64. Atypical forms of acute viral hepatitis

65. Fulminant hepatitis

66. Laboratory diagnosis of acute viral hepatitis

67. Differential diagnosis of acute viral hepatitis

68. Complications and consequences of acute viral hepatitis

69. Prevention of Viral Hepatitis

70. Scarlatina

71. Complications of scarlet fever

72. Treatment and prevention of scarlet fever

73. Erysipelas

74. Treatment and prevention of erysipelas

75. Blain, carbuncle, and malignant staphylococcia of face

76. Staphylococcal and streptococcal toxic shock syndrome

77. Necrotizing fasciitis

78. Measles

79. The diagnosis and differential diagnosis of measles

80. Complications of measles

81. Rubella

82. Complications of rubella

83. Variola

84. Differential diagnosis of rash fever

85. Sepsis

86. The diagnosis and differential diagnosis of sepsis and septic shock

87. The treatment of sepsis and septic shock

88. The clinical picture and treatment of meningococcal sepsis

89. Diagnosis of HIV infection

90. Pulmonary manifestations of AIDS

91. Gastrointestinal manifestations of AIDS

A Guide t 46 o Studies in English - 1st year

92. Neurological manifestations of AIDS

93. The principles of treatment of HIV disease

94. The diagnosis and differential diagnosis of acute retroviral diseases

95. Varicella - herpes zoster

96. Complications of chickenpox

97. Herpes simplex

98. Cytomegalovirus

99. Infectious mononucleosis

100. The diagnosis and differential diagnosis of infectious mononucleosis

101. Enteroviral infection

102. Poliomyelitis

103. Listeriosis

104. Undulant fever

105. Tularemia

106. Plague

107. Anthrax

108. Leprosy

109. Actinomycosis

110. Tetanus

111. Clinical picture and treatment of tetanus

112. Complications of tetanus

113. Anti-tetanus protection

114. Botulism

115. Gas gangrene

116. Toxoplasmosis

117. Malaria

118. Diagnosis and treatment of malaria

119. Malaria chemoprophylaxis

120. Kala-azar

121. Teniasis and cysticercosis

122. Echinococcosis

123. Trihinelosis

124. Intestinal parasitosis

125. Leptospirosis

126. Weil's disease

127. Recurrent fever

128. Borreliosis - Lyme disease

129. Diagnosis and treatment of Lyme disease

130. Spotted typhus and Brill-Zinsser disease

131. Q fever

132. Viral hemorrhagic fever

133. Nosocomial infections

134. Infections in pregnancy

135. Treatment of snakebite

136. Biological warfare and bioterrorism

 

 

TEXTBOOKS

 

1. Infectious diseases in: Harrison's Principles of Internal Medicine, 19th Edition. Eds. Dan L. Longo, MD, Dennis L. Kasper, MD, J. Larry Jameson, MD, PhD, Anthony S.

Fauci, MD, Stephen L. Hauser, MD, Joseph Loscalzo, MD, PhD.

by Mc-Graw-Hill Professional 2015.

2. Harrison's Principles of  Self-assessment and board review, 18^th Edition.

 Eds. Dan L. Longo, MD,  Dennis L. Kasper, MD,  J. Larry Jameson, MD, PhD,  

 Anthony S. Fauci, MD,  Stephen L. Hauser, MD,  Joseph Loscalzo, MD, PhD.

 by Mc Graw-Hill Professional 2012.

3. MIMS' PATHOGENESIS OF INFECTIOUS DISEASE. 6^th Edition.  Anthony  A.

    Nash, Robert G. Dalziel, J. Ross Fitzgerald. by Elsevier 2015

4. Infektivne bolesti, udžbenik za studente medicine. Urednici prof dr

Milena Božić, prof dr Ljubiša Dokić, prof dr Svetlana Nikolić, prof dr Milorad

Pavlović, prof dr Milan Šašić. Beograd, Medicinski fakultet u Beogradu, 2013

 

 

Department of Infectious diseases

University of Belgrade, Faculty of Medicine

Address: Bulevar oslobođenja 16, 11000 Beograd

Phone: +381 11 2683 366

Email:

infektivna.klinika@kcs.ac.rs

milos.korac@med.bg.ac.rs

Course director  Prof. dr Miloš Korać Phone: +381112683366/4355